Natural products derived from a variety of sources may have the tendency to stimulate many physiological pathways which can be beneficial for ailment of stubborn diseases like cancer. Till now, more than 50% of drugs have been designed from natural compounds and, among them, 75% of anticancer drugs were designed and developed from the plant derived natural ingredients. Any of these mechanisms can be targeted by a compound derived from natural source and can be established as a treatment approach. Again there are a number of biomarkers used for diagnostic process. The etiology of breast cancer and proliferation of cancerous cells is generally mediated by a number of mechanisms or pathways. In order to face this deadly situation, many research works are now designed dedicatedly to find out the alternative treatment system of breast cancer which can be used as therapeutics, as an adjuvant treatment besides other treatments, or as chemopreventive agents. Due to this reason, the survival rate of breast cancer patient is very unsatisfactory. One of the most threatening problems with conventional treatment is multidrug resistance (MDR). Some additional factors like side effects of conventional treatment such as chemotherapy and radiotherapy are increasing the burden more and making it more challenging to treat the patients of breast cancer. A number of exogenous and endogenous factors can stimulate the pathology of breast cancer and can worsen the situation. It has become a fatal disease, and risk factors associated with breast cancer seem to be expanding day by day. Future research focusing on the natural anti-breast-cancer agents can open a new horizon in breast cancer treatment, which will play a great role in enhancing the survival rate of breast cancer patients.īreast cancer is an important public health problem worldwide, which is the second most common cancer diagnosed and is also a prime reason of death in women globally. In this review, we discussed some significant natural chemical compounds with their mechanisms of actions, which can be very effective against the breast cancer and can be more potent by their proper modifications and further clinical research. A large number of research works are now focusing on the natural and dietary compounds and trying to find out new and more effective treatment strategies for the breast cancer patients. Natural compounds can fight against aggressiveness of breast cancer, inhibit cancerous cell proliferation, and modulate cancer related pathways. However, adoption of complementary treatment approach can be a big solution for this situation, as it is evident that compounds derived from natural source have a great deal of anticancer activity. Due to severe side effects and multidrug resistance, these treatment approaches become increasingly ineffective. ![]() Hormonal therapy, surgery, chemotherapy, and radiotherapy have been used as treatment of breast cancer, for a very long time. ![]() ![]() Among all types of cancer, breast cancer is one of the most challenging diseases, which is responsible for a large number of cancer related deaths.
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